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Welcome to TUBIC—the Tianjin University BioInformatics Center. Currently, TUBIC is one of the key websites for life sciences of the Ministry of Education, China, and a partner of China National Center for Bioinformation (CNCB). This Bioinformatics center offers a number of services based on the bioinformatics software tools developed by members of TUBIC during the past years. These software tools include those for ab initio gene-recognition (ZCURVE_B) and replication origin prediction in genomes of bacteria, archaea, and budding yeast (Ori-Finder, Ori-Finder 2 and Ori-Finder 3), gene-identification for virus genomes, and especially for coronavirus genomes (ZCURVE_CoV). Additionally, TUBIC also hosts some online databases, such as the Z-curve database (Zcurve_DB), the Database of Essential Genes (DEG), the database of replication origins (DoriC), and the database listing potential G-quadruplex regulated genes (Greglist). Now TUBIC serves as one of the windows to display the achievements of Bioinformatics research in China. TUBIC.ORG is the mirror site of TUBIC. |
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| Special issue on Z-curve applications in genome analysis | |||||||||||||||||||
 Editorial (Thematic Issue:
Z-curve Applications in Genome Analysis) A brief review: the
Z-curve theory and its application in genome analysis Recognition of
protein-coding genes based on Z-curve algorithms Recent advances in the
identification of replication origins based on the Z-curve method Identification of
horizontally-transferred genomic islands and genome segmentation points by using the GC profile
method |
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| Resource at TUBIC | |||||||||||||||||||
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Publications copyright©TUBIC 2022