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Welcome to TUBIC-- the Tianjin University BioInformatics Centre. Currently, TUBIC is one of the key websites for life sciences of the Ministry of Education, China. This Bioinformatics center offers a number of services based on Bioinformatics softwares developed at TUBIC during the past few years. These softwares include those for gene-finding in the yeast genome ZCURVE_Y, ab initio gene-recognition ZCURVE_B and gene-start prediction GS-Finde in bacterial and archaeal genomes, gene-identification for virus genomes, and especially for coronavirus genomes. Additionally, TUBIC also hosts four databases: the Z-curve databaseZcurve_DB, displaying the Z-curves for more than 1000 genomes, the Database of Essential Genes (DEG) for microbial genomes, the database of replication origins in bacterial genomes (DoriC), and the database listing potential G-quadruplex regulated genes Greglist. Now TUBIC serves as one of the windows to display the achievements of Bioinformatics research in China. |
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| Special issue on Z-curve applications in genome analysis | |||||||||||||||||||
 Editorial (Thematic Issue: Z-curve Applications in Genome Analysis) A brief review: the Z-curve theory and its application in genome analysis Recognition of protein-coding genes based on Z-curve algorithms Recent advances in the identification of replication origins based on the Z-curve method Identification of horizontally-transferred genomic islands and genome segmentation points by using the GC profile method |
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| Resource at TUBIC | |||||||||||||||||||
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Publications copyright©TUBIC. 2001.7